Malarone (atovaquone proguanil): Reviews and patient testimonials

Malarone

Malarone is a fixed dose combination of atovaquone and proguanil hydrochloride which acts as a blood schizonticide and also has activity against hepatic schizonts of Plasmodium falciparum. It is indicated for:

Prophylaxis of Plasmodium falciparum malaria.

Treatment of acute, uncomplicated Plasmodium falciparum malaria.

Because Malarone is effective against drug sensitive and drug resistant P. falciparum it is especially recommended for prophylaxis and treatment of P. falciparum malaria where the pathogen may be resistant to other antimalarials.

Official guidelines and local information on the prevalence of resistance to antimalarial drugs should be taken into consideration. Official guidelines will normally include WHO and public health authorities' guidelines.

Malarone Paediatric Tablets

Malarone paediatric tablets contain a fixed dose combination of atovaquone and proguanil hydrochloride, which acts as a blood schizontocide and also has activity against hepatic schizonts of Plasmodium falciparum. They are indicated for:

Prophylaxis of P. falciparum malaria in individuals weighing 11-40 kg.

Treatment of acute, uncomplicated P. falciparum malaria in children weighing ≥5 kg and <11 kg.

For treatment of acute, uncomplicated P. falciparum malaria in individuals weighing 11-40 kg please refer to the Summary of Product Characteristics for Malarone tablets.

Malarone may be active against P. falciparum that are resistant to one or more other antimalarial agents. Therefore, Malarone may be particularly suitable for prophylaxis and treatment against P. falciparum infections in areas where this species is known to be commonly resistant to one or more other antimalarial agents and also for treatment of patients infected with P. falciparum malaria whilst in these areas.

Official guidelines and local information on the prevalence of resistance to antimalarial drugs should be taken into consideration. Official guidelines will normally include WHO and public health authorities' guidelines.

Route of administration: Oral
Molecule: atovaquone, proguanil