Home
Share
Forum
Psoriasis Forum
Treatments for psoriasis
Future technology could make psoriasis pills, injections obsolete

Back

Patients Psoriasis

Future technology could make psoriasis pills, injections obsolete

42 views
0 support
2 comments

Gilda

Community manager

16/02/2016 at 10:39

Good advisor

Gilda

Community manager

Last activity on 03/02/2023 at 15:26

Joined in 2015

710 comments posted | 32 in the Psoriasis Forum

Rewards

Good Advisor
Contributor
Messenger
Committed
Explorer
Evaluator

View profileView Add a friendAdd Write

Researchers have developed a novel cell-based strategy for the treatment of psoriasis. Their synthetic biology–based gene circuits “can autonomously couple the detection of disease biomarkers with the production of therapeutic proteins,” according to a study published December 16, 2015 in Science Translational Medicine.

“Implanted designer cells detect the onset of psoriatic flares by measuring the psoriasis-associated proinflammatory cytokines TNF and IL22 in the bloodstream and produce, secrete and systemically deliver the anti-inflammatory cytokines il4 and IL10 which prevents psoriatic flares or cures them. Thus, the cytokine converter converts pro-inflammatory cytokines (TNF and IL22) into anti-inflammatory cytokines (IL4 and IL10),” the study’s senior author Martin Fussenegger, Ph.D., professor of biotechnology and bioengineering, ETH Zurich, in Switzerland, told Dermatology Times.

In a study of mice, the designer cells prevented psoriatic flare onset, stopped acute psoriasis, improved psoriatic skin lesions and restored normal skin-tissue morphology.

If it pans out in humans, the technology could be a game-changer for dermatologists and their psoriasis patients, according to Dr. Fussenegger.

“In the future, dermatologists could implant engineered autologous cells containing the cytokine converter and the implanted device takes full control of the therapy,” Dr. Fussenegger says. “Biologics such as IL4 and IL10 have proven promising in clinical trials, but the half-lives has been found to be too short for an economic therapy. Cell-based in situ production of biopharmaceuticals by implanted designer cells at the right time and dose will expand treatment opportunities of biologics.”

Dr. Fussenegger and colleagues have plans to develop this technology for human clinical trials.

“If successful, we expect this device to go commercial within the next 10 years,” he says.

What do you think about this innovation? What is your current treatment? Do you think this one can work?

Dermatology Times

All comments

magicmick

11/07/2018 at 18:26

Good advisor

magicmick

Last activity on 12/09/2024 at 21:52

Joined in 2018

39 comments posted | 30 in the Psoriasis Forum

Rewards

Good Advisor
Contributor
Committed
Explorer
Newsfeeder

View profileView Add a friendAdd Write

like so many treatments they use to treat psoriasis there are the side effects on the human system good or bad. it is alright them coming up with a new drug tested on mice but until they actually do the human testing on someone who has psoriasis how can they say it will work or not .it is true that biogenetics could be the way forward but only if they were to map the DNA of the individual person to the treatment to reduce the side effects and the body building up an immunity to the treatment over time .

Future technology could make psoriasis pills, injections obsolete https://www.carenity.co.uk/forum/psoriasis/the-treatments-for-psoriasis/future-technology-could-make-psoriasis-pills-injections-obsolete-797 2018-07-11 18:26:27

thelicencee

31/07/2018 at 12:11

Good advisor

thelicencee

Last activity on 11/12/2024 at 00:23

Joined in 2015

18 comments posted | 3 in the Psoriasis Forum

2 of their responses were helpful to members

Rewards

Good Advisor
Contributor
Committed
Explorer

View profileView Add a friendAdd Write

@GildaT

10 YEARS

This is way to long to wait for this or any other treatments to reach the patient's.

It is about time that 'NICE' ""STOPPED"" considering the COST OF THE TREATMENT, before the WELFARE OF THE PATIENT.

That way MILLIONS of lives could be SAVED or changed for the better.

A classic example of.. BUREAUCRACY OVER LIFE.

Where a group of 'prominent people' get to decide IF 'sick or ill people' can have 'life changing\life saving' medication.

The 'government' are elected into power 'BY THE PEOPLE, TO REPRESENT THE PEOPLE'

NOT

Elected by the people(the majority) to do what is better for THEM(the minority).

It's no wonder that that Britain is NO LONGER 'GREAT BRITAIN'.

It won't be long until Britain becomes 'reliant' on other countries hand outs and support to remain a viable country.

How sad that our once GREAT BRITISH EMPIRE is gradually but constantly disappearing, right before our eyes, yet we fail to see or believe it.

So as the saying goes,

You will reap what you sow.

Members are also commenting on...

Articles to discover...

29/10/2024 | News

Psoriasis complications: What you need to know to better manage the condition!

29/10/2023 | News

Inverse Psoriasis: Everything you need to know!

02/08/2023 | Testimonial

Psoriasis: “Don't do this alone! Open up! Talk about it!”

09/06/2023 | News

Etanercept (Enbrel®, Erelzi®, Benepali®): everything there is to know about this drug!

19/05/2017 | Testimonial

Struggling with hemiplegic migraines, melanoma and psoriatic arthritis

06/02/2015 | Advice

Psoriasis and Psoriatic Arthritis

29/10/2018 | Advice

Our survey results on living with psoriasis

13/06/2018 | Testimonial

Psoriasis: Effect on daily life and getting treatment

Future technology could make psoriasis pills, injections obsolete

All comments

Give your opinion

Members are also commenting on...

Articles to discover...

Medication fact sheets - patient opinions...